addiction_medicine

/VA, Dr. Bell
For dependence – need a story about tolerance and withdrawal symptoms.
EtOH detox, choosing between chlordiazepoxide/lorazepam/diazepam
Chlordiazepoxide usually
Long half life of 16-20 hours
Liver function problems, then use lorazepam –
As lorazepam is glucoridinated, and requires less processing by the liver
(-) short half life of 12-14 hours
Diazepam
Really long half life of 50hours; so can get withdrawal 10 days out from last use
Opiate detox
Can still get autonomic instability (incr BP, incr HR), but not as dramatic as alcohol withdrawal